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MDMA-Assisted Psychotherapy for PTSD: Lessons from Phase 2 Clinical Trials and Beyond
Michael Mithoefer, M.D., and Annie Mithoefer, B.S.N.
Saturday, April 22, 2017 • 3:00 PM - 4:00 PM • East Hall

Continuing Education (CE)Continuing Medical Education (CME) • 0.5 Credits

This presentation will review the results from MAPS Phase 2 clinical trials of MDMA-assisted Psychotherapy for PTSD, with an emphasis on the recently completed study of military veterans, firefighters and police officers with service-related PTSD. Along with the quantitative results indicating significant improvements in PTSD symptoms and other measurable changes, we will present a short video clip and quotes from participants illustrating some of the benefits of MDMA-assisted psychotherapy that go beyond reduction in PTSD symptoms to include effects on relationships, occupational and social functioning and personal growth. There will also be updates of the ongoing MAPS study that allows MDMA research therapists to have their own legal MDMA session in the same context used in treatment studies, and of the ongoing study combining MDMA-assisted psychotherapy with Cognitive Behavioral Conjoint Therapy (CBCT) for PTSD in which both members of a couple receive MDMA together in two psychotherapy sessions during a course of CBCT.

mithoefer Michael Mithoefer, M.D., and Annie Mithoefer, B.S.N.

Michael Mithoefer, M.D., is a psychiatrist in Charleston, SC, who for many years has specialized in treatment of post-traumatic stress disorder (PTSD) with an emphasis on experiential methods of psychotherapy, and is now focusing primarily on MDMA clinical research. He is board certified in Psychiatry, Emergency Medicine and Internal Medicine and is a Grof certified Holotropic Breathwork Practitioner, a Certified Internal Family Systems Therapist and is trained in EMDR. He and his wife, Annie Mithoefer, completed the first clinical trial of MDMA-assisted psychotherapy in 2008 for people with treatment-resistant PTSD. In 2016 they completed a similar study in military veterans, firefighters, and police officers with PTSD. They are currently conducting further MAPS-sponsored MDMA trials and MAPS trainings for therapists who will work in Phase 3 clinical trials and other MDMA research in the US and other countries. Michael is Lead Clinical Investigator and Medical Monitor, MDMA-Assisted Psychotherapy for PTSD, at MAPS Public Benefit Corporation.

Annie Mithoefer, B.S.N., is a psychiatric nurse in Charleston, SC who has many years experience working with individuals with posttraumatic stress disorder (PTSD) using experiential psychotherapies. She is a Grof certified Holotropic Breathwork Practitioner and is trained in Hakomi Therapy. She and her husband, Michael Mithoefer, completed the first clinical trial of MDMA-assisted psychotherapy in 2008 for people with treatment-resistant PTSD. In 2016 they completed a similar study in military veterans, firefighters and police officers with PTSD. They are currently conducting further MAPS-sponsored MDMA trials and MAPS trainings for therapists who will work in Phase 3 clinical trials and other MDMA research in the US and other countries.


Continuing Medical Education (CME) is available for physicians. This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Institute for Medical Quality/California Medical Association (IMQ/CMA) through the joint providership of CME Consultants and the Multidisciplinary Association for Psychedelic Studies (MAPS). CME Consultants is accredited by the IMQ/CMA to provide continuing medical education for physicians.

This activity is geared towards Psychiatrists and Primary Care Physicians.

DESIRED OUTCOMES: 1) Inform their patients about research into treatments for treatment-resistant PTSD 2) Develop strategies for conducting their own research into this experimental method 3) Evaluate research on PTSD treatments as new literature becomes available 4) Develop strategies for treating combat veterans with PTSD, an underserved population 5) Apply aspects of the therapeutic methods developed in MDMA-assisted psychotherapy research to other methods of therapy

*This activity will encompass the following desirable physician attributes: Patient Care & Procedural Skills, Medical Knowledge, Professionalism, Interpersonal & Communication Skills, and Practice-Based Learning & Improvement.

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